Influence of Various Bases on Clinical Efficacy and Safety of Drugs
- VernacularTitle:不同盐基对药物临床效果和安全性的影响分析
- Author:
Song FANG
;
Xiangru LIAO
- Publication Type:Journal Article
- Keywords:
Bases;
Pharmacokinetics;
Pharmacodynamics
- From:
China Pharmacist
2014;(12):2131-2133
- CountryChina
- Language:Chinese
-
Abstract:
Salt formation is the most important method for increasing druggability of active pharmaceutical ingredients ( API) . Nowadays, API containing different bases are emerging continuously. In this paper, the influence of various bases on the pharmacokinetics, pharmacodynamics and side effects of drugs was reviewed, which can provide reference for the selection of clinical therapeutic drugs and the base choice for new drugs.
