Effects of electro-acupuncture at Neiguan, Xinshu, Guanyuanshu points on cardiac function after acute myocardial ischemia in rabbits
10.3760/cma.j.issn.1673-4246.2014.12.014
- VernacularTitle:电针内关、心俞及关元俞对急性心肌缺血兔心功能的影响
- Author:
Yuhong TANG
;
Yuan YAO
;
Desen CHEN
;
Lihong GUO
- Publication Type:Journal Article
- Keywords:
Acupuncture;
Myocardial ischemia;
Malondialdehyde;
Creatine kinase;
Ventricular function
- From:
International Journal of Traditional Chinese Medicine
2014;(12):1104-1106
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of electro-acupuncture at Guanyuanshu, Xinshu, Neiguan points on cardiac function after acute myocardial ischemia in rabbits. Methods A total of 36 rabbits were randomly divided into a control group, a model group and a treatment group. Acute myocardial ischemia was induced with Jugular vein injection of pituitrin. At 10 min before modeling, 1 hour and 1 week after modeling, the levels of malondialdehyde (MDA) and creatine kinase(CK) were determined respectively, the cardiac function was assessed as the maximum rate of left ventricular pressure rise(dp/dtmax)and the peak left ventricular pressure (LVSP). Results After 1 week of treatment, the serum levels of CK and MDA in the treatment group reduced significantly(120.21±10.67 U/L, 21.35±2.04 mmol/L], compared to the model group (162.37±13.21 U/L, 30.13±2.75 mmol/L) (all P<0.05);the dp/dtmax and LVSP decreased percentage in the treatment group (20%±2.43%, 7.22%±0.97%) decrease significantly compared to the model group (31.5%± 4.14%, 12.19%±2.21%) (all P<0.05). Conclusion Electro-acupuncture of Guanyuanshu, Xinshu, Neiguan acupoints can significantly improve cardiac function after acute myocardial ischemia and protect against acute myocardial ischemia in rabbits.
