Clinical Efficacy Observation on Jiuwei Zhenxin Granules in the Treatment of Generalized Anxiety Disor-der
- VernacularTitle:九味镇心颗粒治疗广泛性焦虑障碍疗效观察
- Author:
Jie LIANG
- Publication Type:Journal Article
- Keywords:
Jiuwei Zhenxin granules;
Paroxetine;
Generalized anxiety disorder
- From:
China Pharmacist
2014;(12):2078-2079
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the curative effect and security of Jiuwei Zhenxin granules in the treatment of generalized anxiety disorder. Methods:Totally 112 patients with generalized anxiety disorder were randomly divided into the research group and the control group with 56 ones in each. The research group was given Jiuwei Zhenxin granules while the control group was given paroxetine with the treatment course of 6 weeks. The curative effect of the two groups was observed using Hamilton anxiety scale ( HAMA) , and the side effects were observed using treatment energent eymptom scale( TESS) . Results:After the 2-week treatment, HAMA scores were signifi-cantly lower than those before the treatment (P<0. 01). HAMA scores between the two groups before the treatment and at each time point after the treatment had no statistically significant differences (P>0. 05). The recovery rate and effective rate of the two groups also showed no statistically significant differences (P >0.05). The incidence of adverse drug reactions in the research group was 14. 8%, which was lower than that in the control group (22. 6%, P<0. 05). There was no statistically significant difference in TESS total score between the two groups (P>0. 05). Conclusion:Jiuwei Zhenxin granules show similar effect with paroxetine in the treat-ment of generalized anxiety disorder with lower adverse reaction incidence and promising safety.
