Efficacy Observation of A Clotrimazole Combined with Ultrasonic Atomization of Ozone in the Treatment of Candidal Vaginitis
- VernacularTitle:甲克霉唑联合超声波臭氧雾化治疗念珠菌性阴道炎疗效观察
- Author:
Chunyan ZHONG
;
Lizhi ZHONG
- Publication Type:Journal Article
- Keywords:
Therapeutic apparatus for gynecology with ultrasonic atomization ozone;
Candidal vaginitis;
A clotrimazole
- From:
China Pharmacist
2014;(12):2080-2082
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To observe the efficacy of A clotrimazole combined with ultrasonic atomization of ozone in the treatment of candidal vaginitis. Methods:Totally 200 cases of candidal vaginitis were divided into the observation group and the control group with 100 cases in each. The control group was given A clotrimazole creams through vaginal administration, qd, while the observation group was treated by ultrasonic atomization of ozone additionally, qd, 15min per time with five times. The clinical efficacy and the recurrence rate after 6 months of the two groups were compared. Before the treatment and in the first and fourth week after the treatment, vaginal secretion bacterial culture was performed and pH value was detected. Results:The cure rate and the total effective rate of the observa-tion group was 88% and 98%, respectively, which was significantly higher than that of the control group (69% and 82%, respective-ly, P<0. 05). After the 6-month follow-up, the recurrence rate was 1. 0% in the observation group (1/98), which was significantly lower than that in the control group [7. 3%(6/82),P<0. 05]. After the treatment, the vaginal pH value in the observation group was reduced notably and the number of lactobacillus was increased significantly(P<0. 05), while those in the control group were without significant changes (P>0. 05). Conclusion:A clotrimazole combined with ultrasonic atomization of ozone in the treatment of candidal vaginitis can improve the therapeutic effect.
