Current progress of erythropoietin in depression
10.3969/j.issn.1001-1978.2014.12.003
- VernacularTitle:促红细胞生成素抗抑郁作用研究进展
- Author:
Junling LI
;
Yubo LI
;
Xiaoxing XUE
;
Jinglu YAN
;
Weiming WANG
;
Huihui ZHAO
;
Wei WANG
- Publication Type:Journal Article
- Keywords:
erythropoietin;
depression;
neuranagenesis;
anti-inflammatory;
anti-apoptosis;
derivative
- From:
Chinese Pharmacological Bulletin
2014;(12):1635-1638
- CountryChina
- Language:Chinese
-
Abstract:
Erythropoietin (EPO),which is routinely used in clinic to treat anemia,has been implicated in a wide range of activities on diverse tissues.Recently,accumulating evidence shows that EPO has antidepressant-like effects and may be a po-tential drug candidate for treating mood symptoms and memory dysfunction in depression.This review summarizes the current progress on EPO’s antidepressant-like effects,and explores its potential mechanism and clinical application in the future,provi-ding a general view of the research and application status of EPO in depression.
