Role of micro RNA-106b-25 in cancer
10.3969/j.issn.1001-1978.2014.12.004
- VernacularTitle:Micro RNA-106b-25簇与肿瘤
- Author:
Xi DONG
;
Guibo SUN
;
Xiaoyan XING
;
Xiaobo SUN
- Publication Type:Journal Article
- Keywords:
miRNA;
1 06b-25 cluster;
tumor;
apoptosis;
pro-liferation;
cell cycle
- From:
Chinese Pharmacological Bulletin
2014;(12):1639-1641
- CountryChina
- Language:Chinese
-
Abstract:
Micro RNA (miRNA)were small RNAs encoded by the non-coding RNA genes,which functioned through degrada-tion of mRNA or inhibition of mRNA translation.The miRNA was involved in numerous biological processes,including cell proliferation,apoptosis,development and differentiation.And ectopic expression of miRNA could result in diseases,such as neoplastic hematologic disorder and solid tumor.miR-1 06b-25 cluster contained miR-1 06b,miR-93 and miR-25.These miR-NAs were correlated with the development of tumor.Therefore, we reviewed recent articles on the relationship of miR-1 06b-25 cluster with tumor.
