A novel molecular point-of-care testing detection technology for infectious pathogens:GeneXpert
10.3760/cma.j.issn.1009-9158.2014.11.006
- VernacularTitle:感染病原体新型分子检测技术 GeneXpert
- Author:
Jiayun LIU
;
Xiaoke HAO
- Publication Type:Journal Article
- Keywords:
Point-of-care systems;
Bacteriological techniques;
Molecular diagnostic techniques;
Mycobacterium tuberculosis;
Tuberculosis;
Reagent kits,diagnostic
- From:
Chinese Journal of Laboratory Medicine
2014;(11):820-823
- CountryChina
- Language:Chinese
-
Abstract:
GeneXpert is an advanced molecular biological detection system developed in recent years, it integrates and automates the sample preparation , nucleic acid purification, gene amplification, results report of the fluorescent quantitative PCR process.As, an accurate, rapid, biosafe technology , GeneXpert has become one of the novel molecular POCT detection technology platforms for diagnosis of infectious pathogens and especially declared it a major milestone for global TB diagnosis .This paper introduces the detection principle , clinical application in the detection of infectious pathogens , limitation and prospect of GeneXpert.