Comparison of High Volume Zero-Balanced Ultrafiltration With Different Replacement Fluid in Infant Patients
10.3969/j.issn.1000-3614.2014.11.016
- VernacularTitle:两种不同超滤置换液在患儿大容量零平衡超滤中的比较
- Author:
Fan CAO
;
Guodong HUANG
;
Huili YUAN
;
Nan BAI
;
Huaizhen WANG
;
Xinxin CHEN
- Publication Type:Journal Article
- Keywords:
Zero-balanced ultraifltration;
Plasmalyte A;
Cardiopulmonary bypass
- From:
Chinese Circulation Journal
2014;(11):917-920
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To compare the clinical effects of high volume zero-balanced ultraifltration (ZBUF) with different replacement lfuid in infant patients.
Methods: A total of 40 infant patients who received aortic coarctation with deep hypothermic circulatory arrest operation in our hospital from 2012-11 to 2014-02 were summarized. The patients were randomized into 2 groups, Group A, the patients had ZBUF with plasmalyte A, n=21 and Group B, the patients had ZBUF with modiifed replacement lfuid n=19. All patients received ZBUF (15-20) ml/kg during re-warming period until the temperature reached 34°C at rectum. Blood gas analysis were conducted at 4 time points as T1 (before CPB), T2 (open ascending aorta and 5 min after calcium perfusion), T3 (ifnishing ZBUF) and T4 (end of CPB). The intra-operative CPB time and the post-operative recovery with the complication were recorded in all patients.
Results: For blood gas analysis, the calcium concentration was higher in Group B than that in Group A at T3 time point, P<0.01 and the base excess was higher in Group A than that in Group B at T3 time point, P<0.05. Those indexes were similar at T1, T2 and T4, all P>0.05. The other indexes were similar between 2 groups, P>0.05 and the post-operative recovery was similar between 2 groups, P>0.05.
Conclusion: ZBUF with modiifed replacement lfuid could avoid decreased calcium concentration and acidosis, therefore, provide a relative stable homeostasis in infant patients.
