Review the Function and Structure of Interleukin-35 and Its Function in Mediating Treg Cell Immuno-Suppression
10.3969/j.issn.0253-9896.2014.12.026
- VernacularTitle:IL-35结构功能及其调控Treg细胞免疫抑制功能的研究进展
- Author:
Yongjia YAN
;
Xianghui HE
- Publication Type:Journal Article
- Keywords:
T-lymphocytes,regulatory;
autoimmune diseases;
immune tolerance;
IL-35;
iTR35 cells
- From:
Tianjin Medical Journal
2014;(12):1243-1245
- CountryChina
- Language:Chinese
-
Abstract:
Interleukin (IL)-35 is a new member of IL-12 family who is secreted by T regulatory cells to strongly sup?press immuno reaction directly or indirectly. There is a growing interest in the using IL-35 as a potential therapy for chronic in?flammatory , cancer and autoimmune diseases. Here we reviewed IL-35 and its function as a mediator of suppression.
