Relationship Between Myocardial Ischemia and Left Ventricular Diastolic Function by Fractional Flow Reserve Evaluation in Patients With Coronary Artery Disease
10.3969/j.issn.1000-3614.2014.11.007
- VernacularTitle:血流储备分数评价心肌缺血与左心室舒张功能关系的研究﹡
- Author:
Wei XIE
;
Hong QIU
;
Junming LIU
;
Weixian YANG
;
Ke LI
;
Fengbo REN
;
Qi ZOU
;
Liang ZHAO
;
Na LI
- Publication Type:Journal Article
- Keywords:
Coronary artery disease;
Left ventricular diastolic function;
Coronary angiography;
Fractional lfow reserve
- From:
Chinese Circulation Journal
2014;(11):884-887
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To explore the relationship between myocardial ischemia and left ventricular diastolic function (LVDF) by fractional lfow reserve (FFR) evaluation in patients with coronary artery disease (CAD).
Methods: A total of 57 patients with chest pain were studied, the diagnosis of CAD was confirmed by coronary angiography, which indicated 50%-70%of coronary stenosis. All patients received FFR examination and they were divided into 2 groups:Experimental group, the patients with FFR<0.80, n=27 and Control group, the patients with FFR≥0.80, n=30. The basic condition and risk factors affecting LVDF were compared between 2 groups. Echocardiography was conducted for evaluating left ventricular end-diastolic dimension (LVEDD), left atrial dimension (LAD), left ventricular ejection fraction (LVEF) and E/e ' value in both groups.
Results: The patients’ gender, age, history of hypertension, diabetes, blood levels of cholesterol, TG, LDL-C, HDL-C and glucose were similar between 2 groups, P>0.05. Compared with Control group, the Experimental group had the increased LVEDD, LAD and E/e ' value and decreased LVEF, all P<0.05.
Conclusion: The impact of CAD on early diastolic function depends on functional myocardial ischemia in relevant patients.
