The Epidemiological Characteristics of High Serum Level of Homocysteine in Kazakh Population at Xinyuan County of Xinjiang
10.3969/j.issn.1000-3614.2014.11.015
- VernacularTitle:新疆哈萨克族人血清同型半胱氨酸分布特征及高同型半胱氨酸血症流行特征﹡
- Author:
Hongrui PANG
;
Jingyu ZHANG
;
Shangzhi XU
;
Rulin MA
;
Heng GUO
;
Jiaming LIU
;
Mei ZHANG
;
Yusong DING
;
Shugang LI
;
Shuxia GUO
- Publication Type:Journal Article
- Keywords:
Kazakh;
Serum Homocysteine;
High homocysteinei;
Prevalence
- From:
Chinese Circulation Journal
2014;(11):913-916
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To observe the characteristics of serum homocysteine (Hcy) distribution and the epidemiological characteristics of high serum level of Hcy (HHcy) in Kazakh population.
Methods: The stratiifed cluster random sampling method was used to investigate 1003 kazakh individuals in Xinyuan county of Xinjiang including 433 male and 570 female, and they were individuals into 5 age groups:①(25-34) years, n=333,②(35-44) years, n=306, ③(45-54) years, n=230, ④(55-65) years, n=90, ⑤>65 years, n=44. The questionnaire survey, physical check-up and blood biochemical examination were performed and compared among different groups.
Results: ① The geometrical mean of Hcy was 13.3μmol/L, and the male was higher than female as 16.0μmol/L vs 11.6μmol/L. ②By age stratiifcation, the serum levels of Hcy elevated with the increased age accordingly. Except for those with the age>65 years, the serum levels of Hcy were all higher in male than female in other 4 age groups. ③The average rate of HHcy prevalence was 31.5%, and the male was higher than female as 49.9%vs 17.5%.④The average rate of H type hypertension prevalence was 35.1%, and the male was higher than female as 44.3%vs 28.1%. There were 87.6%of H type hypertensive patients with H type hypertension, and the male was higher than female as 95.0%vs 80.0%, all P<0.001.
Conclusion: The serum levels of Hcy were different from gender and age; the prevalences of HHcy and H type hypertension were higher in Kazakh population at Xinyuan county of Xinjiang. Community intervention should be conducted to improve the public health condition in Kazakh population.
