A clinical control study of error monitoring in the patients with schizophrenia
10.3760/cma.j.issn.1674-6554.2014.11.007
- VernacularTitle:精神分裂症患者错误监测功能的临床对照研究
- Author:
Liangjun PANG
;
Yongmei WANG
;
Qi YANG
;
Bao HUANG
;
Jing DAI
;
Gangqiang SUN
;
Binbin CHEN
;
Rui TAO
- Publication Type:Journal Article
- Keywords:
Schizophrenia;
Error monitoring;
Anterior cingulate cortex
- From:
Chinese Journal of Behavioral Medicine and Brain Science
2014;(11):983-985
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the error monitoring function damages on the patients with schizo?phrenia ( SCH) . Methods A total of 32 patients with schizophrenia were compared with matched 34 health con?trols ( HC) on the error monitoring tasks which were compiled by E?Prime. Results The comparison between SCH group ((713.22±174.52)ms,( 491.14±170.29) ms,( 1060.31±130.84) ms,(8.28±12.55)time,( 8.00± 7.53)time respectively) and HC group ((560.73±156.94) ms,(395.62±188.03) ms,(989.85±104.33) ms, (2.97±4.13) times,(3.12±6.50) times) on the reaction time of choice,assessment,incongruent condition,the numbers of uncertain and the numbers of dropout were significant ( t=-3.737, P=0.000;t=-2.159, P=0.035;t=-2.426, P=0.018;t=-2.282, P=0.022;t=-2.824, P=0.006) . The SCH group and HC group did not signifi?cantly difference in Full Correct((124.72±23.74)/(131.74±21.96)times),Full Error((15.69±17.64)/(13.35± 18.63)times),Part Correct((6.83±10.40)/(4.21±7.03)times),Part Error((2.91±10.91)/(0.62±1.10)times) and Accuracy((0.831±0.161)/(0.874±0.159))(P>0.05).There was no significantly correlation among the course of disease,HAMA,HAMD and the error monitoring. Conclusion These results demonstrate that the error monitoring function damages on the patient with SCH may be involved in the dysfunction of anterior cingulate cortex.
