Recent effects of radiotherapy combined with gastroscopic radiofrequency for advanced esophageal cancer
- VernacularTitle:胃镜腔内射频联合放疗治疗晚期食管癌近期疗效分析
- Author:
Jing WANG
;
Jie LI
;
Fuli ZHANG
;
Ping ZHANG
- Publication Type:Journal Article
- Keywords:
Gastroscopy;
Radiofrequency;
Radiotherapy;
Esophageal cancer;
KPS
- From:
Journal of Chinese Physician
2014;(z2):26-28
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the recent effects of radiotherapy plus gastroscopic radiofrequency for advanced esophageal cancer.Methods The date of 53 patients were retrospectively reviewed.The obstruction of the same period, endoscopic classifica-tion, pathology staging similar in 53 patients with advanced esophageal cancer were contrasted .All patients underwent conventional ra -diotherapy.The treatment group: the first day radiofrequency and afterwards within 8 hours the start of radiotherapy.Results The median time to appear the eat obstruction improvement for the combined group was the fourth day and the eighteenth day for the control group.The difference between two groups was statistically significant ( P <0.05).The improved rate of KPS for the combined group was 37.7% after the first week.For the contrasted group no improvement was observed .The stability of two groups was respectively 62.3% and 100%.After the second week, the improved rate of KPS was 75.5% for the combined group and 11.3% for the contras-ted group, and the stability was 24.5% and 88.7%, respectively.Both had the statistically significant ( P <0.05).The third week later the improved rate became 84.9% and 43.4%, the stability 15.1% and 56.6%.The statistically significant ( P <0.05) was for both groups.After the fourth week the improved rate for both groups of patients was 92.5% and 88.7%, the stability was 7.5% and 11.3%.There was no difference in statistically significant ( P >0.05).The objective alleviation rate after esophagus pathology radio -therapy, for the combined group, was 96.2% and 88.7% for the contrasted group.No difference in statistically significant ( P >0.05) was for both groups.1-year local control rate was respectively 69.8% and 56.6%.The survival rate was 75.5% and 62.3%. There was no difference in statistically significant ( P >0.05).Conclusions The treatment of radiofrequency in gastroscopy chamber can rapidly improve the patients'eating situation, enhance the patients'fitness, enable the smooth radiotherapy, and make a good foun-dation for the concurrent radiotherapy and chemotherapy to improve the effect on the treatment to esophageal cancer .
