"Effect of smoking on""destructive""blood lipid before PCI in male coronary artery disease"
10.3969/j.issn.1673-4130.2014.23.004
- VernacularTitle:吸烟对PCI术前男性冠状动脉心脏病“破坏性”血脂的影响
- Author:
Xin YU
;
Yuankui CHU
;
Xuevo HAN
;
Zhen YANG
;
Yiqing ZHANG
;
Rong MA
- Publication Type:Journal Article
- Keywords:
coronary heart disease;
smoking;
blood lipid
- From:
International Journal of Laboratory Medicine
2014;(23):3162-3164
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the effect of smoking on blood lipid before percutaneous coronary intervention(PCI)in male coronary heart disease(CHD).Methods The clinical data in 124 cases of CHD with PCI were randomly extracted and divided into the smoking group (n = 88 )and the non-smoking group (n = 36 ).The age,past disease history,triglycerides (TG),cholesterol (CHOL),low density lipoprotein(LDL)and high density lipoprotein(HDL)were retrospectively investigated.Results The LDL level of the smoking group was(3.1±1.34)mmol/L,which was significantly higher than(2.5 ±0.95)mmol/L in the non-smoking group with statistical difference between them(P <0.05);the level of TG,HDL and LDL in the CHOL≥4.5 mmol/L group were (2.5±1.49)mmol/L,(0.99±0.29)mmol/L and(3.6 ±1.13)mmol/L respectively,which were hither than(1.8 ±1.23)mmol/L, (0.88±0.20)mmol/L and(2.2±0.69)mmol/L in the CHOL≤4.5 mmol/L group respectively,the differences among them had statistical significance(P <0.05 );the Sperman analysis found that there was a positive correlation between the level of vascular change with CHOL and LDL,at the same time the smoking level was negatively correlated with LDLA.Conclusion Smoking, CHOL and LDL have a close relationship with the male coronary heart disease.Moreover,smoking can affect the lipid metabolism and probably increase the risk of coronary heart disease.
