The therapeutic value of endoscopic papillectomy for adenoma in major duodenal papilla
10.3760/cma.j.issn.1007-5232.2014.11.005
- VernacularTitle:内镜下十二指肠乳头切除术对十二指肠乳头部腺瘤的治疗价值
- Author:
Xiaoling ZHENG
;
Wei LIANG
;
Chaoying FANG
;
Wanyin DENG
;
Jinhui ZHENG
;
Liping HE
- Publication Type:Journal Article
- Keywords:
Endoscopic papillectomy;
Tumor;
Major duodenal papilla
- From:
Chinese Journal of Digestive Endoscopy
2014;(11):634-637
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the therapeutic value of the endoscopic papillectomy for adenoma in the major duodenal papilla.Methods All 3 1 cases with the major duodenal papilla undergoing endoscopic papillectomy from January 2008 to June 2013 were retrospectively reviewed.The clinical data,endoscopic treatment,complications and follow-up were analysed.Results Endoscopic papillectomy was performed successfully in 29 patients.Post-operative pathology showed adenoma with low-grade dysplasia in 25 cases and high-grade dysplasia in 4 cases.One patient (3. 4%,1/29 )bled during operation;and there was no bleeding after operation. There was no perforation during and after the operation. Seventeen patients (58. 6%,17/29)developed hyperamylasemia and 3 patients(10. 3%,3/29)got mild pancreatitis,which were cured by conservative treatment.During follow-up,2 patients (6. 9%,2/29)with high-grade dysplasia had tumor recurrence after 6 months and 2 years respectively.The 27 other patients had no recurrence during the follow-up period.The shortest follow-up was 1 1 months,the longest was 5 years,with a mean time of 33. 5 ±8. 5 months.Conclusion Endoscopic papillectomy is feasible and safe for early tumors of the major duodenal papilla.Although the postoperative recurrence rate is low,it still needs close follow-up.