Analysis of detection results of bone alkaline phosphatase in 2 184 children in Baoji area
10.3969/j.issn.1673-4130.2014.23.033
- VernacularTitle:宝鸡地区2184例儿童骨碱性磷酸酶结果的分析
- Author:
Zhengmei QIAO
;
Junli GE
;
Qiujian ZHAO
;
Liqiang ZHANG
- Publication Type:Journal Article
- Keywords:
children;
bone alkaline phosphatase;
rickets
- From:
International Journal of Laboratory Medicine
2014;(23):3228-3229
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the clinical value of bone alkaline phosphatase in early diagnosis and treatment effect of chil-dren′rickets and to understand the incidence rate of rickets in children in the local region by the detection of neonatal bone alkaline phosphatase(NBAP).Methods 2 184 children with physical examination in our hospital from January to December 2013 were se-lected and divided into the infants,young children,preschool and school-age children groups according to age.The finger blood was collected for detecting the bone alkaline phosphatase in the peripheral blood by the bone alkaline phosphatase reagent kit provided by Beijing Jinyu diagnosis technology Co.,Ltd.Results Among detected 2 184 children,the detection rate of clinical rickets(NBAP>250 U/L)was 10.1 %,moreover the smaller the age,the higher the detection rate;the detection rate of subclinical rickets(NBAP 200~250 U/L)was 65.5%,indicating that most children in Baoji region were in sub-health state;the detection rate in spring and winter was higher than that in summer and autumn;the detection rate of NBAP had no gender difference.Conclusion Children are in the rapid growth and development period,easy to suffer from vitamin D deficiency,the activity detection of NBAP has important clinical value in the early diagnosis of rickets caused by vitamin D deficiency.Prevention should begin from perinatal period and NBAP should be timely detected in order to conduct early diagnosis and early treatment.
