Research progress of miR-451 in tumor
10.3760/cma.j.issn.1673-422X.2014.12.003
- VernacularTitle:微小RNA-451在肿瘤中的研究进展
- Author:
Yang NAN
;
Yue ZHONG
- Publication Type:Journal Article
- Keywords:
Neoplasms;
MicroRNAs
- From:
Journal of International Oncology
2014;41(12):887-890
- CountryChina
- Language:Chinese
-
Abstract:
MicroRNA-451 (miR-451) is significantly lowly expressed in glioma,gastric cancer,colorectal cancer,liver cancer and other tumor tissues.Upregulation of miR-451 can significantly inhibit tumor cell proliferation,invasion and metastasis as well as increasing tumor cell apoptosis and improving radiotherapy and chemotherapy sensitivity and other biological effects.