The role of microRNAs in breast cancer stem cells
10.3760/cma.j.issn.1673-422X.2014.12.002
- VernacularTitle:微小RNA在乳腺癌干细胞中的作用
- Author:
Changfei MAO
;
Jianzhong WU
;
Jinhai TANG
- Publication Type:Journal Article
- Keywords:
MicroRNAs;
Neoplastic stem cells;
Breast neoplasms
- From:
Journal of International Oncology
2014;41(12):884-887
- CountryChina
- Language:Chinese
-
Abstract:
Cancer stem cells are a kind of cancer cell group with the ability of self-renewal and various diferentiation potentials.Recent studies have implicated that they play a significant role in tumor formation,metastasis,resistance to anticancer therapies and cancer recurrenee.Many studies show that microRNAs are involved in the maintenance,growth and behavior of breast cancer stem cells (BCSCs),paving a new way for diagnosis,prognosis and therapy of breast cancer.