Efficacy and safety evaluation of half quantity of tirofiban on elderly patients with ST segment elevation myo-cardial infarction
10.3760/cma.j.issn.1008-6706.2014.23.005
- VernacularTitle:半量替罗非班用于老年人 ST 段抬高型心肌梗死的疗效及安全评价
- Author:
Xin ZENG
- Publication Type:Journal Article
- Keywords:
Tirofiban;
Myocardial Infarction;
Angioplasty,transluminal,percutaneous coronary;
Aged
- From:
Chinese Journal of Primary Medicine and Pharmacy
2014;(23):3533-3534
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate clinical efficacy and safety of half quantity of tirofiban on elderly patients with ST segment elevation myocardial infarction ( STEMI ) .Methods 120 elderly patients with STEMI underwent emergency PCI patients,120 cases of digital method were randomly divided into the control group and observation group,60 cases in the control group with conventional surgery and drug treatment,the observation group of 60 cases on the basis of conventional therapy was given to half the amount for tirofiban,the two groups were observed in the risk of bleeding, the occurrence of adverse cardiovascular events after operation.Results The postoperative bleeding risk of the observation group compared with the control group had no significant difference(χ2 =1.51,1.35, 0.94,P=0.643,0.768,0.578);for the observation group in 30 days after operation,90 days of re infarction,death and target vessel revascularization rate compared with the control group decreased,the difference was statisticallysig-nificant(30 days after operation,χ2 =9.54,18.33,16.75,P=0.043,0.029,0.031;90 days after operation,χ2 =17.48,21.78,19.54,P=0.034,0.011,0.021).Conclusion Semi quantity for tirofiban can reduce the risk of elderly patients with STEMI after PCI,improve clinical outcome,which will not increase the risk of hemorrhage.
