Clinical research on the effects of propranolol on infantile hemangiomas

VernacularTitle:口服普萘洛尔治疗婴幼儿血管瘤的临床研究
Author: Jun GUO ; Yu WANG ; Jing YU
Publication Type:Journal Article
Keywords: propranolol; infantile hemangiomas; curative effect
From: Chongqing Medicine 2014;(33):4464-4466
CountryChina
Language:Chinese
Abstract: Objective To study the efficacy and adverse reactions of the treatment on different types of infantile hemangiomas (IH) with different doses of propranolol .Methods One hundred and fifty cases of IH without contraindications were randomly treated with different doses of propranolol (low dose group:1 mg?kg -1 ?d-1 ;high dose group:2 mg?kg -1 ?d-1 ) under ECG monitoring inferior half an hour to breastfeeding taking ,and stay in hospital for observation for 6 to 24 hours after the treatment . The patients returned to the hospital for review every month(ECG and blood RT ;lung function in necessary) .Results The curative effect is better on strawberry IH than that on flat IH ,also better on deeply IH than that on superficial IH .The adverse reactions oc‐curred relatively slight in the low dose group and there was no significantly statistical differences on the treatment effects between the both groups(P>0 .05) .Conclusion It is safe and effective to treat IH with propranolol .