Evaluation of the role of contrast enhanced ultrasound in treatment of ultrasound guided high intensity focused ultrasound ablation for uterine fibroids
10.3969/j.issn.1671-8348.2014.33.018
- VernacularTitle:六氟化硫微泡造影在高强度聚焦超声治疗子宫后壁肌瘤中的作用评价
- Author:
Li LIN
;
Xiaofang LIU
;
Jia HE
- Publication Type:Journal Article
- Keywords:
high intensity focused ultrasound;
uterine fibroids;
contrast enhanced ultrasound;
sulphur hexafluoride micro bubbles
- From:
Chongqing Medicine
2014;(33):4469-4471
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the role of contrast enhanced ultrasound in treatment of ultrasound guided high intensity fo‐cused ultrasound ablation for uterine fibroids .Methods Forty eight women with uterine fibroids were allocated into contrast en‐hanced group(25cases ,42fibroids) and non contrast enhanced group(23 cases ,35 fibroids) .The average volume of fibroids and the non perfused volume and the fractional ablation and adverse effects between the tow groups were compared .Results Non perfused volume was observed in all fibroids of the two groups after high intensity focused ultrasound ablation through sulphur hexafluoride micro bubbles .The average non perfused volume was 19 .5(18 .2)cm3 and 22 .5(14 .5)cm3 ,fractional ablation was (78 ± 18)% and (87 ± 13)% of the uterus immediately after HIFU respectively .The average non perfused volume was 18 .6(18 .2)cm3 and 19 .5 (18 .7)cm3 ,fractional ablation was (85 .7 ± 15 .2)% and (87 .6 ± 8 .0)% of the uterus two days after HIFU .There was no signifi‐cant difference was observed in average non perfused volume and the fractional ablation between the two groups(P>0 .05) .During HIFU procedure ,more patients in non contrast enhanced group complained sacral pain than those in contrast enhanced group(P<0 .05) .Conclusion Contrast enhanced ultrasound is an accurate method in assessing the treatment effect of HIFU and could be safely used during HIFU treatment for uterine fibroids ,shorten therapy time ,and decrease side reaction .
