Serum level of galectin 3 and its clinical significance in patients with chronic kidney disease
10.3969/j.issn.1671-8348.2014.33.014
- VernacularTitle:慢性肾脏疾病患者血清半乳糖凝集素-3检测的临床意义
- Author:
Dong LAI
;
Yongmei XIONG
;
Min LONG
;
Yiqin ZHANG
- Publication Type:Journal Article
- Keywords:
galectin 3;
chronic kidney disease;
renal function
- From:
Chongqing Medicine
2014;(33):4460-4461
- CountryChina
- Language:Chinese
-
Abstract:
Objective To detect serum galectin 3 levels in patients with chronic kidney disease (CKD) and explore its clinical significance .Methods The galectin 3 levels the serum of in 38 CKD patients and 34 healthy controls were determined by ELISA . All kidney function was measured by automatic biochemical analyzer .The relation between serum galectin 3 levels and the level of kidney function was analyzed by use of t test .Results The serum galectin 3 levels in CKD and healthy controls groups were (1 .22 ± 1 .01)ng/mL and (3 .03 ± 2 .06)ng/mL ,P<0 .05 .There was close negative correlation between serum levels of galectin 3 and Cr ,CysC(P<0 .05) .Conclusion Serum galectin 3 of CKD patients reduces significantly and correlates with kidney function . Detecting on s galectin 3 is helpful for chronic kidney disease diagnosis and therapeutic effect evaluation .
