Molecular diagnosis of childhood tuberculosis: history and present
10.3760/cma.j.issn.2095-428X.2014.22.002
- VernacularTitle:儿童结核病分子生物学诊断进展
- Author:
Chaomin ZHU
;
Yun PAN
- Publication Type:Journal Article
- Keywords:
Mycobacterium tuberculosis;
Child;
Molecular diagnosis
- From:
Chinese Journal of Applied Clinical Pediatrics
2014;29(22):1683-1686
- CountryChina
- Language:Chinese
-
Abstract:
Childhood tuberculosis remains a serious public health threat which draws more and more attention.The unspecific symptoms or signs and the paucibacillary nature of childhood tuberculosis make it hard to diagnose which delays appropriate treatment and increases disease burden and mortality.Molecular methods such as polymerase chain reaction (PCR),real-time PCR,and DNA line probe based on mycobacterium tuberculosis specific nucleotide sequence will make a quick and reliable diagnosis of childhood tuberculosis.