Diagnostic value ofβ-HCG and fβ-HCG of adverse pregnancy

VernacularTitle:绒毛膜促性腺激素及其游离β亚单位对不良妊娠的诊断价值
Author: Yuzhi YUAN ; Dongwu ZHANG ; Jianquan YU
Publication Type:Journal Article
Keywords: β-HCG; fβ-HCG; adverse pregnancy; progesterone; doubling rate
From: International Journal of Laboratory Medicine 2014;(22):3030-3031
CountryChina
Language:Chinese
Abstract: Objective To explore the diagnostic value of β‐human chorionic gonadotropin (β‐HCG) and its free β‐subunit (fβ‐HCG) of adverse pregnancy .Methods Chemiluminescence technique was used for the detection of serum levels ofβ‐HCG ,fβ‐HCG and progesterone in women with early adverse pregnancy (threatened abortion group ,missed abortion group and ectopic pregnancy group) and normal pregnant women (control group) ,respectively .The 48 h doubling rate ofβ‐HCG of each group was calculated . And the results were analyzed .Results Comparing with threatened abortion group ,there were significant differences in the levels of β‐HCG ,fβ‐HCG ,progesterone and doubling rate both of missed abortion group and ectopic pregnancy group (P<0 .05) .How‐ever ,there was no difference in these indicators between missed abortion group and ectopic pregnancy group ( P> 0 .05 ) . Conclusion T he changes of β‐HCG and fβ‐HCG can reflect adverse pregnancy .