Clinical Observation in Treatment of Diabetic Peripheral Neuropathy by Blood-activating and Qufengchushi Chinese Medicine Lavipeditum with Mecobalamin Tablets
10.3969/j.issn.1005-5304.2014.12.007
- VernacularTitle:活血祛风除湿中药足浴联合口服甲钴胺片治疗糖尿病周围神经病变临床观察
- Author:
Yi ZHANG
;
Min ZHANG
- Publication Type:Journal Article
- Keywords:
lavipeditum;
mecobalamin tablets;
diabetic peripheral neuropathy
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2014;(12):22-24
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the clinical efficacy in treatment on diabetic peripheral neuropathy (DPN) by Chinese medicine lavipeditum of blood-activating and Qufengchushi with mecobalamin tablets. Methods 65 diabetic patients were randomly divided into 2 groups. The two groups were both undertaking the diabetes diet control, exercise, diabetes education and maintaining previous hypoglycemic program. The patients with hypertension could take nifedipine GITS. Patients in control group only received mecobalamin tablet. Patients in treatment group received the same medication and also lavipeditum with Blood-activating and Qufengchushi traditional Chinese medicine for 12 weeks. Clinical symptom score, Toronto clinical score, motor nerve conduction velocity (MNCV) and sensory conduction velocity (SNCV) of median nerve and peroneal nerve were performed before and after the study. Results After treatment, the mean values for clinical symptom score, Toronto clinical score, MNCV and SNCV of median nerve and peroneal nerve of the tweo groups were all significantly decreased (P<0.05, P<0.01). The values for TCM clinical syndromes in treatment group was 81.81% (27/33), and that in the control group was 65.62% (21/32), with significant difference (P<0.05). The values for western medcine clinical syndromes in treatment group was 84.84% (28/33), and that in the control group was 62.50%(20/32), with significant difference (P <0.05). Conclusion Chinese medicine lavipeditum of Blood-activating and Qufengchushi with mecobalamin tablets is safet and effective in treating DPN.