The ReIationship of Mean PIateIet VoIume and Sudden SensorineuraI Hearing Loss
10.3969/j.issn.1006-7299.2014.06.011
- VernacularTitle:突发性聋患者血小板平均体积检测结果分析
- Author:
Xuesong ZHENG
;
Nongsheng HOU
;
Rui HAO
- Publication Type:Journal Article
- Keywords:
Mean platelet volume;
Sudden sensorineural hearing loss;
Thrombotic vascular diseases
- From:
Journal of Audiology and Speech Pathology
2014;(6):600-602
- CountryChina
- Language:Chinese
-
Abstract:
Objective Our aim was to investigate the association between sudden sensorineural hearing loss (SSHL)and mean platelet volume (MPV)values,in order to evaluate the etiology of SSHL.Methods This study included 40 patients with SSHL in our ward between Jan.2012 and Jan.2014 and 30 age- and sex-matched healthy subjects were included as controls.The correlation among the levels of the number of platelets,mean plate-let volume(MPV),platelet distribution width (PDW)was evaluated in the two groups.ResuIts The platelet count was significantly lower in the SSHL than the control group(212.0±47.9 versus 237.8±46.2 ×109/L).MPV and PDW were significantly higher in SSHL(10.9±0.8 versus 10.3±0.8 fL;12.9%±2.0% versus 12.0%±1.3 %). The SSHL patients were divided two subgroups:the mild-moderate subgroup (hearing loss 25~70 dB)and the se-vere subgroup(hearing loss≥70 dB).The MPV values were insignificantly different between the two subgroups(11. 0±1.1 fL versus 10.8 ±1.0 fL).Compared to the control group,the two subgroups had both significant differ-ences in MPV.ConcIusion High MPV values are a risk factor for thrombotic vascular diseases.Considering the in-creased MPV levels,SSHL appears to be characterized by ischaemic or thrombotic events.