Clinical distribution and antimicrobial resistance of 172 Proteus mirabilis isolates and 68 Proteus vulgaris isolates
10.3969/j.issn.1671-9638.2014.12.002
- VernacularTitle:172株奇异变形杆菌和68株普通变形杆菌临床分布及其耐药性
- Author:
Shan LUO
;
Wenen LIU
;
Qun YAN
;
Qingxia LIU
;
Yanming LI
- Publication Type:Journal Article
- Keywords:
Proteus mirabilis;
Proteus vulgaris;
Proteus;
pathogen;
drug resistance,microbial;
rational drug use
- From:
Chinese Journal of Infection Control
2014;(12):710-713
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze strains of Proteus mirabilis (P .mirabilis )and Proteus vulgaris (P .vulgaris ) isolated in a hospital,detect resistance to commonly used antimicrobial agents,and provide reference for rational ap-plication of antimicrobial agents in clinic.Methods 172 P .mirabilis isolates and 68 P .vulgaris isolates isolated between January 1 ,2011 and June 30,2013 were analyzed,antimicrobial resistance susceptibility testing were per-formed by disk diffusion method,data were analyzed with WHONET 5.4 software.Results P .mirabilis strains were mainly isolated from wound secretion(26.74%),sputum(22.68%)and urine(18.61 %),P .vulgaris were mainly from wound secretion(48.53%),urine(17.65%)and sputum(11 .77%).The resistance rates of P .mirabilis to ampicillin and trimethoprim/sulfamethoxazole were both>45.00%;the resistance rates of P .vulgaris to cefazo-lin and trimethoprim/sulfamethoxazole was 86.76% and 41 .18% respectively;the resistance rates of P .mirabilis and P .vulgaris to piperacillin/tazobactam,cefotaxime,ceftazidime,cefepime,carbapenems (ertapenem and mero-penem)and amikacin were all <20.00%.Conclusion The resistance rates of P .mirabilis and P .vulgaris to pip-eracillin/tazobactam,cefotaxime,ceftazidime,cefepime,ertapenem,meropenem and amikacin are all high,and can be used as the empirical medication for the treatment of related infection.
