Comparison of clinical study for thoracolaparoscopic esophagecto-my and open two-field lymph node dissection esophagectomy for stage middle esophageal carcinoma
10.3969/j.issn.1000-8179.20141311
- VernacularTitle:胸腹腔镜与开放手术食管癌切除术二野淋巴结清扫治疗中期食管癌的对比研究
- Author:
Bo LIU
;
Pengfei LIU
;
Mingqiang KANG
;
Xu LI
;
Minglian QIU
;
Fancai LAI
- Publication Type:Journal Article
- Keywords:
esophageal neoplasms;
thoracoscopy;
laparoscopy;
two-field lymph node dissection
- From:
Chinese Journal of Clinical Oncology
2014;(24):1577-1581
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To explore the security and the radical and clinical value of thoracoscopic-laparoscopic esophagectomy with two-field lymph node dissection for middle esophageal cancer through comparison with open esophagectomy. Methods: A total of 410 stage II to stage III esophageal cancer patients who underwent two-field lymph node dissection with two different methods (thora-colaparoscopic esophagectomy and open esophagectomy) from January 2009 to July 2013 in Uninon Hospital, Fujian Medical Universi-ty, were analyzed retrospectively. General pathological parameters, operative procedures, and short-term outcomes were collected and compared between the two groups (TLG and OG). Results: No significant differences were found regarding general pathological pa-rameters, such as gender, age, etc. Significant differences between thoracolaparoscopic and open two-field lymph node dissection esoph-agectomy were observed in terms of esophagectomy intraoperative blood loss [(206 ± 138) mL vs. (240±111) mL] and the mean num-ber of dissected lymph node per person [(26.6±8.6)/per vs. (21.7±9.2)/per]. Overall postoperative morbidity rate in OG was 35.2%, and its difference from that of TEG (25.8%) is statistically significant (P<0.05). Regarding single complications, such as pulmonary infec-tion and arrhythmia, OG showed evidently superior results (P<0.05). Meanwhile, anastomotic stricture and hoarseness rate are higher in TEG (P<0.05), and the difference was statistically significant as well. Conclusion: Thoracolaparoscopic two-field esophagectomy is technically feasible and safe and can achieve radical tumor resection.