Study of the values of renal function indicators in predicting chronic kidney disease
10.3969/j.issn.1673-4130.2014.22.012
- VernacularTitle:肾功能指标对慢性肾病的预测价值研究
- Author:
Min WANG
;
Jie GU
;
Hua CAO
- Publication Type:Journal Article
- Keywords:
chronic kidney disease;
renal function;
cystatin C;
β2-microglobulin
- From:
International Journal of Laboratory Medicine
2014;(22):3034-3035
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss the values of renal function indicators in predicting chronic kidney disease (CKD) .Methods According to eGFR ,212 cases of CKD patients were divided into three groups :group A (eGFR> 60 mL · min-1 · 1 .73 m -2 ) , group B (eGFR 30-60 mL · min-1 · 1 .73 m-2 ) ,and group C (eGFR<30 mL · min-1 · 1 .73 m-2 ) .175 cases of patients with the risk of CKD and 60 cases of healthy people were selected at the same time and brought into high‐risk group and normal control group ,respectively .The ratios of microalbumin and creatinine in urine (UmAlb/Cr) ,and the serum levels of Urea ,creatinine(Cr) , uric acid(UA) ,cystatin C(CysC) ,β2‐microglobulin(BMG) and homocysteine(Hcy) in all the groups were detected .Results There were differences in the levels of CysC and BMG among the three groups of CKD patients(P<0 .05) ,as well as between high‐risk group and normal control group ,with significant difference (P<0 .05) .Conclusion CysC and BMG can be used as effective indica‐tors of CKD prediction .
