Application of ROC curve to determine the ELISA cut-off value for the diagnosis of alveolar echinococcosis
10.3969/j.issn.1673-4130.2014.22.038
- VernacularTitle:应用ROC曲线分析确定ELISA法检测泡型包虫病的诊断界值
- Author:
Yanhong LI
;
Yousen ZHU
;
Zhaoxia ZHANG
- Publication Type:Journal Article
- Keywords:
ROC curve;
enzyme linked immunosorbent assay;
alveolar echinococcosis;
cut-off value
- From:
International Journal of Laboratory Medicine
2014;(22):3090-3091
- CountryChina
- Language:Chinese
-
Abstract:
Objective To determine the ELISA cut‐off value for the diagnosis of alveolar echinococcosis by applying ROC curve . Methods 34 cases of alveolar echinococcosis specimens confirmed by the gold standard were selected and detected by ELISA .The diagnostic cut‐off value was determined by ROC curve ,and the sensitivity and specificity were calculated according to the cut‐off value .Results When the cut‐off value was 0 .44 ,the ROC curve had the largest area under the curve (AUC) accounting of 0 .995 , and the sensitivity and specificity w ere 97 .06% and 97 .06% respectively .Conclusion T he ROC curve is the best w ay to determine the cut‐off value of ELISA .
