Relationship between ADC value of MR diffusion-weighted imaging and histological differentiation grade of rectal tubular adenocarcinoma
10.3969/j.issn.1002-1671.2014.11.019
- VernacularTitle:直肠管状腺癌磁共振扩散加权成像 ADC 值与肿瘤分化程度的关系
- Author:
Changchun CHEN
;
Zilong YUAN
;
Xiaofang GUO
;
Xian CHEN
;
Yulin LIU
- Publication Type:Journal Article
- Keywords:
rectal cancer;
tubular adenocarcinoma;
magnetic resonance imaging;
diffusion-weighted imaging;
apparent diffusion coefficient
- From:
Journal of Practical Radiology
2014;(11):1848-1850
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the diffusion-weighted imaging (DWI)characteristics and the correlation of diffusion coeffi-cient (ADC)and differentiation grade of rectal tubular adenocarcinoma.Methods The DWI characteristics of thirty-eight patients pathologically comfirmed rectal tubular adenocarcinomas were evaluated respectively.There were 9 highly differentiated tubular ade-nocarcinomas,1 5 moderately differentiated tubular adenocarcinomas and 14 poorly differentiated tubular adenocarcinomas.The ADC value was calculated from two different factors (0 and 1 000 s/mm2 ).The correlation between ADC value and the differentiated de-gree of tumour was statistically analysed.Results The mean ADC for highly differentiated group was (0.92±0.05)×10 -3 mm2/s, and the mean ADC for moderately differentiated group was (0.79 ± 0.10)× 10 -3 mm2/s whereas that for poorly differentiated group was (0.71±0.06)×10 -3 mm2/s.The difference among three groups was statistically significant(P <0.05).The ADC value and the differentiated degree of tumour were negatively correlated(Spearman r =-0.704)P<0.01.Conclusion DWI and ADC value can be a useful estimating for the differentiation of rectal tubular adenocarcinoma.
