Comparison of non-steroidal anti-inflammatory drugs after posterior lumbar fusion surgery
10.3969/j.issn.1006-5725.2014.20.042
- VernacularTitle:非甾体类抗炎镇痛药在腰椎后路内固定术后镇痛效果的比较
- Author:
Shuaihao HUANG
;
Qiujian ZHENG
;
Yisheng WANG
;
Changxiang LIANG
;
Mengmeng TIAN
- Publication Type:Journal Article
- Keywords:
Posterior lumbar fusion surgery;
Flurbiprofen Axetil;
Parecoxib sodium;
Postoperative pain management
- From:
The Journal of Practical Medicine
2014;(20):3321-3323
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the analgesia effect and the safety of Flurbiprofen Axetil (FA) and Parecoxib Sodium (PS) after posterior lumbar fusion surgery. Methods 90 patients undergoing internal fixation of lumbar spine randomly assigned to 3 groups:those in Group A(n = 30) received 100 mg of FA; those in Group B (n=30) received 40 mg of PS and those in Group C received saline.The VAS scores of 2, 6, 12, 24, 48, 72 h after operation and the dose of tramadol hydrochloride (TH) used and the side effect was recorded respectively. Results Group A and B had significantly better analgesic effect than Group C(P<0.05). Group A and B had lower average dose of TH than Group C (P<0.05). The VAS scores in Group A was lower than that in Group B in 2 h after the surgery. The VAS scores after the surgery showed no significant difference between Group A and B in 6 , 12, 24 h after the surgery. The VAS scores in Group A was higer than that in Group B in 48,72 h after the surgery. Conclusion Both PS and FA can alleviate postoperative pain and have fewer adverse reactions.
