Effects of pentazocine on intubation stress response during slow induction of anesthesia
10.3969/j.issn.1006-5725.2014.20.043
- VernacularTitle:喷他佐辛在健忘镇痛慢诱导麻醉中对气管插管应激反应的影响
- Author:
Guoli LI
;
Wei WANG
;
Wei LIU
;
Jinliang TENG
;
Fulong LI
- Publication Type:Journal Article
- Keywords:
Pentazocine;
Fentanyl;
Slow induction of anesthesia;
Stress Response
- From:
The Journal of Practical Medicine
2014;(20):3324-3326
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of pentazocine combined with midazolam on intubation stress response in slow induction of anesthesia. Mtheods Forty ASAⅠ~Ⅱpatients were divided into two groups. Anesthesia was induced with midazolam 0.03 mg/kg in both groups,and pentazocine 0.8 mg/kg (i.v.) was given in pentazocine group or fentanyl 2 μg/kg (i.v.) in fentanyl group. Five minutes later, 2 mL of 1% decicaine was administered by cricothyroid membrane puncture to facilitate the intubation.The SpO2, circulatory indexes (HR, SBP, DBP, BIS) and sedation level were measured at T0, T1, T2, T3, T4, T5, T6. Results Both pentazocine and fentanyl can inhibit stress responses to tracheal intubation effectively,but pentazocine group is better than fentanyl group on the cardiovascular stability during slow induction of anesthesia. Conclusion Pentazocine 0.8 mg/kg can inhibit stress responses to tracheal intubation effectively with a low incidence of adverse reactions in the slow induction of anesthesia.
