Prediction value of procalcitonin for acute kidney injury in patients with acute pancreatitis
10.3969/j.issn.1006-5725.2014.20.045
- VernacularTitle:降钙素原预测急性胰腺炎患者急性肾损伤发生的价值研究
- Author:
Xianhe WANG
;
Shengrong PAN
- Publication Type:Journal Article
- Keywords:
Acute pancreatitis;
Acute kidney injury;
Procalcitonin
- From:
The Journal of Practical Medicine
2014;(20):3329-3331
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the clinical value of procalcitonon (PCT) for predicting development of acute kidney injury and outcomes in patients with acute pancreatitis (AP). Methods 205 inpatients with acute pancreatitis in our hospital were enrolled in our study during January 2012 to March 2013. According to acute kidney injury (AKI) occurred in three consecutive days or not, the patients were divided into AKI group (n = 32) and control group (n=173). Crea, Urea, CysC and PCT, serum amyloid A (SAA), interleukin-6 (IL-6) and C reactive protein (CRP) were analyzed. The predictive validity of these indicators was constructed by receiver operating characteristics (ROC) curve. Results PCT, IL-6, and CRP level of AKI group showed significant higher in AKI group than control group (P<0.05). However, there were no statistically significant difference of the level of Urea, Crea, Cys C and SAA between the two groups (P>0.05). The AUC value of PCT showed significant higher than the AUC value of CRP, IL-6 and SAA(P<0.05). Conclusion PCT is a early, sensitive, specific biomarker for predicting AKI of patients with AP.
