Advances in Study on Immunological Factors in Drug-induced Liver Injury
10.3969/j.issn.1008-7125.2014.11.001
- VernacularTitle:药物性肝损伤的免疫学研究进展
- Author:
Lu ZHOU
;
Bangmao WANG
- Publication Type:Journal Article
- Keywords:
Drug-InducedLiverInjury;
Autoimmunity;
CytochromeP-450EnzymeSystem;
Hepatitis,Autoimmune
- From:Chinese Journal of Gastroenterology
2014;(11):641-643
- CountryChina
- Language:Chinese
-
Abstract:
The pathogenesis of drug-induced Iiver injury( DILI)remains uncIear. AccumuIating evidences in recent years showed that immunoIogicaI factors pIay important roIe in the pathogenesis of DILI. In this articIe,we summarized recent studies on immunoIogicaI factors invoIved in pathogenesis of DILI and compared the immunity mediated DILI with drug induced autoimmune hepatitis. The advances in study on immunoIogicaI factors in DILI wiII have significant impact on prevention and treatment of DILI and autoimmune hepatitis.
