Correlation of atherosclerotic renal artery stenosis with coronary artery disease and peripheral arterial disease:a Meta-analysis
10.3969/j.issn.1671-8348.2014.35.015
- VernacularTitle:动脉粥样硬化性肾动脉狭窄与冠状动脉病变及外周血管病变关系的Meta分析
- Author:
Bo LIU
;
Luxiang CHI
;
Jianfeng LV
;
Zhizhou SU
;
Hua XIAO
;
Gang WANG
;
Mengyu REN
- Publication Type:Journal Article
- Keywords:
coronary artery disease;
renal artery obstruction;
peripheral arterial disease;
case-control studies
- From:
Chongqing Medicine
2014;(35):4751-4754
- CountryChina
- Language:Chinese
-
Abstract:
Objective To systematically evaluate the relationship between atherosclerotic renal artery stenosis (ARAS) and cor‐onary artery disease (CAD) and peripheral arterial disease (PAD) .Methods We gathered all case‐control studies about the correla‐tion of ARAS with CAD and PAD in the following databases:Cochrane library ,PubMed ,EMBASE ,Web of science until April , 2014 .Two reviewers extracted all relevant datas from the screened documents independently according to exclusion and inclusion criteria ,RevMan 5 .2 software were used to conduct Meta‐analysis .Results Fourteen trials were included .Meta‐analysis showed that :the OR (95% CI)of CAD with 1 vascular lesions ,2 vascular lesions ,3 vascular lesions and left main stenosis ,PAD and ARAS were 0 .70(0 .59-0 .82) ,1 .28(1 .10 -1 .48) ,2 .09(1 .69 -2 .59) ,1 .82(1 .40 -2 .36) ,3 .68(2 .21 -6 .10) with statistical signifi‐cance (P<0 .05) .Conclusion CAD with 2 vascular lesions ,3 vascular lesions and left main stenosis ,PAD were connected with ARAS ,CAD with 1 vascular lesions has little relationship with ARAS .
