Research of HPV infection situation of 12 196 gynecological clinic patients in Chongqing
10.3969/j.issn.1671-8348.2014.35.013
- VernacularTitle:重庆地区12196例妇科门诊患者HPV亚型感染情况分析
- Author:
Chunhui YAN
;
Lin CHEN
;
Manli YUAN
;
Xiao ZHOU
- Publication Type:Journal Article
- Keywords:
human papillomavirus;
multiple infection;
age;
infection type
- From:
Chongqing Medicine
2014;(35):4746-4748
- CountryChina
- Language:Chinese
-
Abstract:
Objective To learn the HPV infection situation of gynecological patients ,so as to provide a scientific basis for the epidemiological studies in Chongqing area .Methods Totally 12 196 gynecology clinic patients in January 2010 to December 2013 were registered whose cervical secretions was collected as specimens ,was type testing was carried on by PCR‐reverse dot hybridiza‐tion ,age distribution ,infected type and multiple infection of the patients were counted .Results There were 3 745(30 .8% ) patients with a positive test specimen of 12 196 patients detected in this study ,the high‐risk HPV infection rate was 61 .67% ,the top three high‐risk HPV subtype were HPV58 ,HPV16 and HPV52 ;the low‐risk HPV infection rate was 21 .23% and the main subtypes were HPV6 and HPV43 .The majority of multiple infections was double infection .There were significant differences between each age groups (χ2 =129 .76 ,P<0 .05) ,the paragraph of HPV infection rate present as U shaped curve .Conclusion The HPV in‐fection of gynecology clinic patients in Chongqing area has obvious regional specificity and age differences .HPV58 ,HPV16 and HPV52 should be pay attention in clinical diagnosis .The age group ≤25 and ≥46 years old are two peaks of HPV infections ,and it should be strengthen the screening of the two age groups .
