Distribution of nontuberculous mycobacteria of clinical mycobacterium isolates f rom Fujian Province,China

VernacularTitle:福建省临床分离非结核分枝杆菌菌种分布研究
Author: Mingxiang HUANG ; Kanglin WAN ; Lizhou CHEN ; Lishui ZHANG ; Dan LI
Publication Type:Journal Article
Keywords: nontuberculous mycobacterium; PCR-RFLP; species identification
From: Chinese Journal of Zoonoses 2014;(12):1227-1230
CountryChina
Language:Chinese
Abstract: ABSTRACT:To understand the species distribution of nontuberculous mycobacteria (NTM ) in Fujian Province of China , we collected clinical Mycobacterium isolates in the Fuzhou Pulmonary Hospital from 2009 to 2012 .A total of 6 362 clinical My‐cobacteria isolates were identified as 5 713 (89 .8% ) M .tuberculosis complex and 649 (10 .2% ) NTM strains by conventional identification method .Then ,by means of hsp65‐and rpoB‐PCR‐RFLP methods ,649 NTM strains were identified as 24 spe‐cies or complex of NTM ,in which the top three species or complex with the highest occurrence frequency were M .intracellular , M .avium and M .abscessus ,accounting for 48 .5% ,21 .3% and 12 .5% respectively .The prevalence rate of NTM was 10 .2%among Mycobacterium culture‐positive patients .There are lots of NTM species infecting human being ,and the most prevalence NTM species was M .avium complex accounting for 67 .8% in Fujian Province .