Research progress of norovirus
10.3969/cjz.j.issn.1002-2694.2014.12.016
- VernacularTitle:诺如病毒的研究进展
- Author:
Qiong WU
;
Yulin HE
- Publication Type:Journal Article
- Keywords:
norovirus;
cell culture;
tissue tropism;
epidemiology;
infection mechanism;
detection;
vaccine
- From:
Chinese Journal of Zoonoses
2014;(12):1245-1251
- CountryChina
- Language:Chinese
-
Abstract:
ABSTRACT:Norovirus infection in human and animals can cause acute viral gastroenteritis .With molecular biology ,cell culture and animal models of development ,the different groups of norovirus genome sequenced ,the virus capsid protein ex‐pressed in vitro in eukaryotic ,prokaryotic and plant systems ,and thus the characteristics of the virus with some new under‐standing and perspective .Recently ,an increasing number of studies were focused on the norovirus and related topics along with the research progress all around the world .Here we systematically expound the latest advances in norovirus research from dif‐ferent aspects ,such as genome structure and function ,cell culture ,tissue tropism ,epidemiology ,virus infection mechanism , detection methods and vaccine development .Furthermore ,different viewpoints for norovirus molecular evolution ,detection technology and transmission route will be discussed as well .
