The optimal dose of dexmedetomidine for preventing of shivering during caesarean section under epidural anesthesia
- VernacularTitle:右美托咪定用于防治剖宫产术中寒战反应的适宜剂量
- Author:
Xia WU
;
Chuanbao HAN
;
Xiuhong JIANG
;
Zhengnian DING
- Publication Type:Journal Article
- Keywords:
Dexmedetomidine;
Anesthesia;
Epidural;
Cesarean section;
Shivering
- From:
The Journal of Clinical Anesthesiology
2014;(12):1211-1213
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the optimal dose of dexmedetomidine for preventing of shive-ring during caesarean section under epidural anesthesia.Methods One hundred and twenty ASA Ⅰ orⅡ parturients with a single baby at full term in vertex presentation,scheduled for caesarean section under continuous epidural anesthesia,were randomly divided into 4 groups (n=30 each):group D1, group D2,group D3 and group N (control group).After delivery of the baby,The group D1,group D2 and group D3 were received an intravenous infusion loading dose of 0.2μg/kg,0.5μg/kg and 0.8μg/kg of dexmedetomidine within 10 minutes respectively,and following with an intravenous infusion 0.4 μg·kg-1·h-1 of dexmedetomidine until peritoneal closure.The group N received an intravenous infusion 0.1 ml·kg-1·h-1 of normal saline.Results The incidence and degree of shivering in group D2 and group D3 were lower than those in group D1 and group N(P<0.05),but there were no statistics differences between group D2 and group D3.Conclusion Administration of dexmedetomidine can re-duce the occurrence of shivering during caesarean section under epidural anesthesia,and a loading dose of 0.5 μg/kg of dexmedetomidine is the optimal dose.
