Effect of heating in a calorstat to the oxygen-carrying function of red blood cell
- VernacularTitle:恒温箱加温对库存红细胞悬液携氧能力的影响
- Author:
Xiangfeng WANG
;
Qin LIN
;
Zixin ZHOU
- Publication Type:Journal Article
- Keywords:
Transfusion;
Red blood cells;
2,3-diphosphoglycerate
- From:
The Journal of Clinical Anesthesiology
2014;(12):1234-1236
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the change of the oxygen-carried function of stored red blood cells,which was warmed in room temperature and calorstat.Methods Randomly removed from 4 ℃storage refrigerator,red blood cell suspension were put in room temperature 30 min (group N)and 37℃ calorstat 30 min (group H),and samples taken to examine electrolyte,blood gas,free Hb,ATP content,2,3-DPG content,oxygen affinity(P50).Results In two groups,blood pH value and blood Na+ did not change obviously due to heating.The content of blood K+ and free Hb increased,glucose fell,but there was no statistically significant difference.The content of ATP and 2,3-DPG in eryth-rocyte increased and P50 increased after heating (P <0.05),which increased more significantly in group H compared with group N (P<0.05).Conclusion Heating stored blood up to 37 ℃ can in-crease the oxygen-carried function of red blood cells,which contribute to improve the effectiveness of transfusion.
