Analysis on drug resistance in 78 strains of meticillinˉresistant Staphylococcus aureus
10.3969/j.issn.1673-4130.2014.24.038
- VernacularTitle:78株耐甲氧西林金黄色葡萄球菌的耐药分析
- Author:
Min CAO
- Publication Type:Journal Article
- Keywords:
nosocomial infection;
meticillin-resistant Staphylococcus aureus;
drug resistance gene;
drug resistance rate
- From:
International Journal of Laboratory Medicine
2014;(24):3388-3389
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the drug resistance characteristics of 78 strains of meticillin-resistant Staphylococcus aureus (MRSA)for guiding rational use of antibiotics in clinic.Methods 78 strains of MRSA were collected in our hospital from Septem-ber 2013 to March 2014;their antimicrobial susceptibility test and the drug resistant gene were detected by the MIC method and PCR respectively.Results The resistance of MRSA to erythromycin was more than 90%,which to tetracycline and clindamycin was close to 90%,which to quinolones was more than 70%,which to aminoglycosides was more than 50%,which to trimethoprim and sulphame-thoxazole,nitrofurantoin and rifampicin was lower;no strains were resistant to tigecycline,quinupristin/dalfopristin, vancomycin,linezolid;77 strains of MRSA were positive for mecA gene.Conclusion The drug resistance rate of isolated MRSA in our hospital is roughly the same with that reported,but which still has difference among different departments;clinic should select drugs according to the drug susceptibility test results for preventing aggravation of MRSA drug resistance.
