Research on Effects of Qi-stagnation and Blood-stasis Pattern of Primary Dysmenorrhea Treated by Huo-Xue Li-Qi Zhi-Tong Decoction Combined with Acupuncture
10.11842/wst.2014.11.026
- VernacularTitle:活血理气止痛汤联合针灸治疗原发性痛经气滞血瘀证疗效研究＊
- Author:
Ping ZHOU
;
Yanghong XIANG
;
Ying ZHOU
- Publication Type:Journal Article
- Keywords:
Primary dysmenorrheal;
acupuncture;
Huo-Xue Li-Qi Zhi-Tong decoction;
ibuprofen;
clinical effect
- From:
World Science and Technology-Modernization of Traditional Chinese Medicine
2014;(11):2430-2434
- CountryChina
- Language:Chinese
-
Abstract:
This study was aimed to observe effects of qi-stagnation and blood-stasis pattern of primary dysmenorrhea (PD) treated by Huo-Xue Li-Qi Zhi-Tong (HXLQZT) decoction combined with acupuncture. A total of 130 PD patients, which were selected from January 2011 to January 2014 at the Chongqing Academy of Traditional Chinese Medicine, were randomly divided into the treatment group and the control group, with 65 cases in each group. The control group was treated with ibuprofen sustained release capsules and the treatment group was given HXLQZT decoction combined with acupuncture. After the treatment of 3 menstrual cycles, indexes were observed from aspects including visual analogue score (VAS), PGF2a, PGE2, PGF2a/PGE2, clinical efficacy and relapse circumstance before and after treatment in two groups. The results showed that compared with pretreatment, there were obvious decreased VAS in both the treatment group and the control group (P<0.05), decreased PGF2a, increased PGE2 content, and obvious decreased PGF2a/PGE2 ratio (P < 0.05). Compared with the control group, the cure rate and the total efficiency of the treatment group were significantly increased (P < 0.05). The VAS was significantly decreased in the third menstrual cycle after treatment (P < 0.05). The ratio of PGF2a/PGE2 was significantly decreased (P < 0.05). In the end of 6-month, 9-month and 12-month treatment, relapse rates of the treatment group were significantly lower than those of the control group (P<0.05). It was concluded that HXLQZT decoction combined with acupuncture can regulated the plasma content of PGF2a and PGE2 and reduce the relapse rate among PD patients. It had obvious effect on PD patients with superior treatment effect compared to western medicine treatment. Therefore, it was worthy of a promotion.
