Correlation between hypertensive disorder complicating pregnancy with homocysteine,DˉD and hsˉCRP
10.3969/j.issn.1673-4130.2014.24.018
- VernacularTitle:妊娠期高血压疾病患者与同型半胱氨酸、D-二聚体及超敏C反应蛋白的相关性研究
- Author:
Xirong LI
;
Shaoya HUANG
;
Shifeng ZHOU
- Publication Type:Journal Article
- Keywords:
hypertensive disorder complicating pregnancy;
homocysteine;
high sensitive C-reactive protein;
D-D
- From:
International Journal of Laboratory Medicine
2014;(24):3341-3342
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship between hypertensive disorder complicating pregnancy(HDCP)with homo-cysteine,D-D and high sensitive C-reactive protein(hs-CRP).Methods 80 HDCP women included 38 cases of gestational hyperten-sion,26 cases of mild preeclampsia and 16 cases of severe preeclampsias,and at the same time 36 normal late-term pregnant women and 30 non-pregnant normal women were selected as the control group.The plasma Hcy was determined by the enzymatic cycling assay,D-D was determined by the latex immune turbidimetry and hs-CRP was determined by the nephelometry immuno assay,re-spectively.Results The plasma Hcy,D-D and hs-CRP levels in the HDCP group were significantly increased compared with the normal non-pregnancy women group and the normal late-term pregnancy women group controls and showed the increasing trend with the aggravation of disease condition,the differences had the statistical significance(P <0.01).Conclusion Timely monitoring the plasma Hcy,D-D and hs-CRP levels can effective conduct the adverse pregnancy prediction,thus timely takes the medication in-tervention for correcting the occurrence and development of the disease condition,and provides the significant reference indexes for evaluating the change and prognosis of the disease condition in clinic.
