Efficacy of intratympanic dexamethasone combined with prednisone on idiopathic sudden sensorineural hearing loss
10.3969/j.issn.1006-5725.2014.21.045
- VernacularTitle:鼓室内注射地塞米松联合强的松治疗突发性聋33例
- Author:
Peng LI
;
Yi ZHANG
;
Qiuyang FU
;
Jinghua XIE
;
Yong LIANG
- Publication Type:Journal Article
- Keywords:
Sudden sensorineural hearing loss;
Intratympanic injection;
Dexamethasone
- From:
The Journal of Practical Medicine
2014;(21):3496-3498
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the therapeutic efficacy of intratympanic dexamethasone injections combined with prednisone in patients with idiopathic sudden sensorineural hearing loss. Methods A total of 71 patients diagnosed with sudden hearing loss were treated with intratympanic dexamethasone injections plus prednisone (B group) or prednisone alone (A group). Hearing was evaluated by pure tone audiogram performed before initial treatment and at 4 weeks following the final treatment. Results The total recovery rate after the treatment was 81.8% in the B group and 55.3% in the A group. The diflference between two groups was statistically significant (P < 0.05). Conclusion The present study suggests that sudden sensorineural hearing loss patients treated with intratympanic dexamethasone combined with prednisone have a higher likelihood of hearing recovery than those treated with prednisone alone.
