Value of carotid and lower limbs arteries atherosclerosis in prediction of intracranial atherosclerosis combined with type 2 diabetes

VernacularTitle:颈动脉及下肢动脉硬化在预测2型糖尿病患者合并颅内动脉硬化中的作用
Author: Qingyuan ZHANG ; Li LIU ; Yaoguang WANG ; Weilai CHEN ; Lifen ZHENG ; Mei FENG
Publication Type:Journal Article
Keywords: Diabetes mellitus,type 2; Intracranial atherosclerosis; Carotid artery; Lower limbs arterial
From: The Journal of Practical Medicine 2014;(21):3425-3427
CountryChina
Language:Chinese
Abstract: Objective To investigate the value of carotid and lower limbs arteries atherosclerosis in prediction of intracranial atherosclerosis combined with type 2 diabetes (T2DM). Methods Seventy-four patients with T2DM received the carotid artery , lower limbs arterial color Doppler ultrasound and cranial MRA examination. The data was analysised by Pearson correlation and Binary Logistic methods. Results With the increasement of degree of peri-arterial atherosclerosis , the intracranial arteriosclerosis was in a trend of increase. The correlation coefficients, OR values and AUC of LLAS and CAS + LLAS for intracranial atherosclerosis were 0.28 (P < 0.05) and 0.33 (P < 0.05), 0.14 (P < 0.05) and 9.28 (P < 0.05), 70.30% (P < 0.05) and 70.60% (P < 0.05), respectively. The cut-off point of LLAS and CAS + LLAS was lever 2. Conclusion The LLAS and CAS + LLAS with T2DM are independent risk factors for intracranial atherosclerosis , owning certain forecast values.