Optimization of Extraction Technology of Hyperici Perforate Herba, Coptidis Rhizoma, Schisandrae Chinensis Fructus, and Ziziphi Spinosae Semen forJinzao Yuanzhi Capsule by Orthogonal Test
10.3969/j.issn.1005-5304.2015.01.026
- VernacularTitle:正交试验法优选金枣远志胶囊中贯叶金丝桃等提取工艺
- Author:
Lei LI
;
Hongli LI
;
Hong YAO
- Publication Type:Journal Article
- Keywords:
Jinzao Yuanzhi Capsule;
orthogonal test;
extraction technology;
Hyperici Perforate Herba;
Coptidis Rhizoma;
Schisandrae Chinensis Fructus;
Ziziphi Spinosae Semen
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2015;(1):91-94
- CountryChina
- Language:Chinese
-
Abstract:
Objective To optimize the extraction conditions of Hyperici Perforate Herba, Coptidis Rhizoma, Schisandrae Chinensis Fructus, and Ziziphi Spinosae Semen forJinzao Yuanzhi Capsule.Methods Hyperin extraction rate was set as index, and HPLC was used for determination. The extraction conditions of ethanol concentration, ethanol quantity, extraction time and other factors were studied with orthogonal test and comparative test.Results Ethanol concentration and extracting times were remarkable factors in the test. The optimum extraction technology forJinzao Yuanzhi Capsule was to reflux and extract the materials with 8 times of 70% ethanol for 2 times, reflux extraction for 1.5 hours, filtration. Then 6 times of 70% ethanol was added for 1.5 hours’ reflux, filtering, and merging extracted liquid.Conclusion The optimum extraction technology is reasonable and feasible.
