Content Determination of Sodium Danshensu inBawei Qidan Capsule by HPLC

VernacularTitle:HPLC测定八味芪丹胶囊中丹参素钠含量
Author: Hailan WU ; Xiaoshen SUN ; Mei MENG ; Jing ZHANG ; Ying JIANG
Publication Type:Journal Article
Keywords: Bawei Qidan Capsule; sodium Danshensu; HPLC; content determination
From: Chinese Journal of Information on Traditional Chinese Medicine 2015;(1):95-97
CountryChina
Language:Chinese
Abstract: Objective To establish an HPLC method for the content determination of sodium Danshensu inBawei Qidan Capsule.Methods HPLC was applied and the determination was performed on Shim-pack CLC-ODS C18 column (250 mm×4.6 mm, 5μm) with methanol-water- acetic acid (7∶92∶1, V/V/V) solution at a flow rate of 1.0 mL/min and detection wavelength at 281 nm. The column temperature was 30℃, and injection volume was 10μL.Results Through methodological study, the linear range of sodium Danshensu was 0.494 4-4.944μg (r=0.9996), the average recovery was 97.20%, RSD=1.13%.Conclusion The HPLC method for the content determination of sodium Danshensu inBawei QidanCapsule was user-friendly, accurate and reliable, with good repeatability and stability, which can be used for quality control ofBawei Qidan Capsule.