The diagnostic accuracy of CT angiography for intracranial aneurysms in patients with subarachnoid hemorrhage:a Meta-analysis
10.3969/j.issn.1002-1671.2014.12.004
- VernacularTitle:颅内动脉瘤破裂 CT 血管成像诊断价值的 Meta 分析
- Author:
Yan WU
;
Xuwen ZENG
;
Zhiping LIANG
;
Yuanman TAN
- Publication Type:Journal Article
- Keywords:
cerebral aneurysms;
subarachnoid hemorrhage;
computed tomography;
angiography
- From:
Journal of Practical Radiology
2014;(12):1966-1970
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the value of CT Angiography (CTA)in the diagnosis of cerebral aneurysms in patients with a-cute subarachnoid hemorrhage (SAH )with Meta analysis.Methods A systematic search in PubMed,MEDLINE,EMBASE, CNKI,CBM,WANFANG databases was performed.Criteria for inclusion were established based on validity criteria for diagnostic research published by the Cochrane Methods Group on Screening and Diagnostic.The methodological quality of each study was eval-uated by QUADAS.Meta-Disc Version 1.4 software were used for heterogeneity test and the pooled weighted sensitivity,specifici-ty,positive likelihood ratio,negative likelihood ratio and 95% confidence intervals were calculated,receiver operating characteristic (SROC)and area under the curve(AUC)were obtained with random-effects models.Stata12.0 was used for the funnel plot to ana-lyze publication bias.Results Fourteen studies were included with a total of 1 332 patients and 1 149 ruptured cerebral aneurysms. The pooled weighted sensitivity and specificity of CTA with 95% confidence interval was 0.96(0.95-0.97)and 0.99(0.97-1.00) respectively.The AUC and the Q value of SROC was 0.99 and 0.958 4 respectively.Conclusion CTA has high sensitivity and spe-cificity in the diagnosis of cerebral aneurysms in patients with SAH,can be proposed as an important imaging diagnostic method.
