Progress of animal experimental research on phospholipase A2 in cardiovascular diseases
10.3969/j.issn.1671.7856.2014.012.011
- VernacularTitle:磷脂酶 A2在心血管疾病动物实验中的研究进展
- Author:
Qinqin YANG
;
Minli CHEN
- Publication Type:Journal Article
- Keywords:
Phospholipase A2;
Cardiovascular diseases;
Animal experiments
- From:
Chinese Journal of Comparative Medicine
2014;(12):55-61
- CountryChina
- Language:Chinese
-
Abstract:
Phospholipase A2(PLA2)is a class of enzymes with the ability to catalyze hydrolysis of lipoproteins and glycerophospholipid in the membrane, mainly including secreted PLA2 ( sPLA2 ) , cytosolic PLA2 ( cPLA2 ) , Ca2+-independent PLA2 ( iPLA2 ) and lipoprotein-associated phospholipase A2 ( Lp-PLA2 ) .They are closely related to many diseases.The studies of the role of PLA2 in cardiovascular diseases have been a hot topic in recent years.This paper focuses on the recent advances in research on the effects of PLA2 on cardiovascular diseases in animal experiments.
